PRIMARY SOFT-TISSUE SARCOMA OF THE EXTREMITIES IN ADULTS

Citation
Cp. Karakousis et al., PRIMARY SOFT-TISSUE SARCOMA OF THE EXTREMITIES IN ADULTS, British Journal of Surgery, 82(9), 1995, pp. 1208-1212
Citations number
20
Categorie Soggetti
Surgery
Journal title
ISSN journal
00071323
Volume
82
Issue
9
Year of publication
1995
Pages
1208 - 1212
Database
ISI
SICI code
0007-1323(1995)82:9<1208:PSSOTE>2.0.ZU;2-R
Abstract
The modern literature on adult extremity sarcoma implies that adjuvant therapy (usually irradiation) is mandatory for adequate local control , at least in patients with high-grade tumours undergoing limb-sparing procedures. In 152 primary extremity soft tissue sarcomas, wide or ra dical resection was employed (116 patients) including amputation in ni ne patients (6 per cent), or local excision followed by adjuvant posto perative radiation therapy (36). Local recurrence alone occurred in 5 per cent of patients, and in combination with distant metastases in 9 per cent. The total rate of local recurrence was 10 per cent after wid e resection (with or without chemotherapy) and 25 per cent after conse rvative resection and radiotherapy (with or without chemotherapy). Lim b sparing was possible in 94 per cent of patients. The majority (76 pe r cent) had surgical resection alone as local treatment with satisfact ory results. Wide resection, when feasible, provides acceptable local control and may be preferable to local excision plus radiation therapy .