Mm. Melin et al., PERCUTANEOUS CHOLECYSTOSTOMY - A VALUABLE TECHNIQUE IN HIGH-RISK PATIENTS WITH PRESUMED ACUTE CHOLECYSTITIS, British Journal of Surgery, 82(9), 1995, pp. 1274-1277
Percutaneous cholecystostomy offers a potentially important therapeuti
c modality for critically ill patients with acute cholecystitis who re
present a high risk for general anaesthesia. The aim of the study was
to assess experience with percutaneous cholecystostomy in resolving th
e acute episode of cholecystitis without operative intervention. Twent
y-two consecutive patients with a clinical diagnosis of acute cholecys
titis underwent the procedure. All were at high risk for general anaes
thesia, and all but one developed cholecystitis while hospitalized for
another co-morbid condition; 14 were in an intensive care unit. Twent
y-one of the 22 patients proved to have acute cholecystitis (11 acalcu
lous, ten cholelithiasis). There were no acute technical complications
. Toxaemia resolved in 17 of the 21 patients with acute cholecystitis.
Acute cholecystitis failed to resolve in three patients; all died wit
hin 48 h from overwhelming generalized sepsis. One patient required em
ergency cholecystectomy for bile peritonitis when the cholecystostomy
catheter became dislodged 24 h after placement. The 60-day mortality r
ate for the acalculous and calculous patient groups was 55 and 20 per
cent, respectively. Only three interval cholecystectomies have been pe
rformed at a mean follow-up of 19 months. In conclusion, percutaneous
cholecystostomy may be the procedure of choice for the management of a
cute cholecystitis in the very high-risk critically ill patient. If sy
mptoms fail to resolve quickly, ongoing sepsis, cholangitis or gallbla
dder necrosis should be suspected.