VITAMIN-A CONCENTRATION IN BREAST ADIPOSE-TISSUE OF BREAST-CANCER PATIENTS

Vitamin A concentration in breast adipose tissue as a risk factor for breast cancer was studied by assessing the vitamin A concentration in breast adipose tissue of women with benign breast disease (n = 45) and of those with breast cancer (n = 36). No significant differences in v itamin A concentration between the two groups were found either in pre menopausal or postmenopausal subjects. The same was hue with the dieta ry intake of vitamin A in these two groups of women. The vitamin A con centration in breast adipose tissue had a significant correlation with the dietary intake in breast cancer cases only (r = 0.42, p < 0.01). The present results support the previous suggestion that vitamin A is unlikely to be related to the risk of breast cancer.