SPINDLE-CELL LIPOMAS - A REPORT OF 2 CASES - ONE WITH MULTIPLE LESIONS

BACKGROUND. Spindle cell lipoma is an unusual and histologically disti nctive form of lipoma occurring primarily in older individuals. OBJECT IVE. The dermatologic surgeon and pathologist should be familiar with this variant of lipoma. METHODS. We are reporting two cases of spindle cell lipomas with the results of histologic examination with special stains and immunohistochemical studies. RESULTS. The neoplasms consist ed of lobulated masses of mature adipose tissue with areas of spindle cell proliferation. There was strong positive staining with antibodies for vimentin within the areas of spindle cell proliferation. One of t he cases is unusual in that multiple lesions are occurring in a young patient. CONCLUSION. Recognition of the histologic pattern is importan t in distinguishing the benign spindle cell lipoma from the malignant liposarcoma.