DIVERSITY AMONG LEISHMANIA ISOLATES FROM THE SUDAN - ISOENZYME HOMOGENEITY OF LEISHMANIA-DONOVANI VERSUS HETEROGENEITY OF L-MAJOR

Authors
IBRAHIM ME EVANS DA THEANDER TG ELHASSAN AM KHARAZMI A
Citation
Me. Ibrahim et al., DIVERSITY AMONG LEISHMANIA ISOLATES FROM THE SUDAN - ISOENZYME HOMOGENEITY OF LEISHMANIA-DONOVANI VERSUS HETEROGENEITY OF L-MAJOR, Transactions of the Royal Society of Tropical Medicine and Hygiene, 89(4), 1995, pp. 366-369
Citations number
14
Categorie Soggetti
Public, Environmental & Occupation Heath","Tropical Medicine
Journal title
Transactions of the Royal Society of Tropical Medicine and Hygiene → ACNP
ISSN journal
00359203
Volume
89
Issue
4
Year of publication
1995
Pages
366 - 369
Database
ISI
SICI code
0035-9203(1995)89:4<366:DALIFT>2.0.ZU;2-C
Abstract
Leishmania isolates from patients in the Sudan suffering from either v isceral or cutaneous leishmaniasis were characterized using a battery of 12 enzymes. Aspartate aminotransferase separated the L. donovani is olates into 2 distinct zymodemes, but the overall results showed no si gnificant geographical variation among L. donovani isolates. In contra st, the isolates of L. major were polymorphic, exhibiting differences in nucleoside hydrolase, 6-phosphogluconate dehydrogenase, superoxide dismutase, esterase, mannose phosphate isomerase, and aspartate aminot ransferase, resulting in the description of 4 new enzymatic variants.