Since the introduction of different ovulation induction regimens the i
ncidence of triplet pregnancies increased from a spontaneous rate of a
bout 1:10 000 to the frequency of nearly 1:1000. Sex ratio of trigemin
i and male/female proportion of the three newborns within the same tri
plet set is the amazing issue that we at tempted to elucidate in the p
resent study. Data on 36 women with triplet pregnancies delivered in o
ur hospital and information regarding 2717 tripler pregnancies reporte
d by 16 relevant papers were included in this study. 36 women delivere
d 63 (58%) male and 45 (42%) female babies. Triplet sets of same gende
r comprised 33% of all trigemini. Sex ratios (male/female) for the spo
ntaneous, menotropin and clomiphene group were 2.00, 1.57 and 0.94 res
pectively. Homogenous male/female set ratio was 5.0, 2.0 and 0.5 in me
notropin, spontaneous and clomiphene groups respectively. As the perce
ntage of ovulation induction triplet pregnancies increased constantly
from 0% to 100%, a decline in the fraction of homogenous gender triple
t sets was observed - from 73% to 23%. It may be concluded that sex ra
tio in triplet newborns is divergent according to different publicatio
ns with most of the authors reporting a male/female ratio of less than
1.00. Ovulation induction results in a lower proportion of homogenous
sex triplets sets. Superovulation by menotropins cause a higher perce
ntage of male triplet newborns when compared to ovulation induction by
clomiphene.