Thirty patients with incurable malignant obstruction of the oesophagus
and cardia were treated with self expanding oesophageal memory metal
stents (Ultraflex) in a prospective study. The endoprostheses were suc
cessfully placed in all patients. Within one week after implantation d
ysphagia had improved in 25 of 30 patients (83%). Stent expansion was
incomplete within one week after implantation in 12 of 30 patients (40
%). After an average of two dilatation sessions eight of 12 stents had
expanded completely. Five patients complained of retrosternal pain an
d three of them suffered from heartburn over several days despite acid
inhibition. Major problems in the follow up period occurred in 10 of
30 patients (30%) and included late perforation (one) and tumour ingro
wth/overgrowth (nine). All of these complications were treated endosco
pically. Improvement of the dysphagia of the with tumour ingrowth/over
growth lasted for about eight weeks (median; range: 2-38 weeks). Until
November 1994 six of 30 patients were still alive with a survival tim
e of 309 days (median; range: 103-368 days). It is concluded that oeso
phageal memory metal stents are easy to implant, prove effective in th
e palliation of malignant oesophageal obstructions, and have a low ris
k of severe complications. The only disadvantages are that incomplete
initial stent expansion as well as tumour ingrowth/overgrowth occurred
in nearly one third of the patients.