Between January 1988 and April 1994, simultaneous carotid endarterecto
my and myocardial revascularization were performed in 20 patients (16
men and 4 women) with a mean age of 67.38 +/- 11 years (range: fifty-s
ix to seventy-eight years). The neurologic presentations included asym
ptomatic carotid bruit in 4 patients (20%), history of transient ische
mic attack (TIA) in 11 (55%), and previous stroke with recent history
of TIA in 5 (25%). Preoperatively, 14 patients (70%) were in New York
Heart Association functional class III, with the remainder in either c
lass I (5%) or class II (25%). Coronary arteriography demonstrated sev
ere coronary atherosclerosis involving a double-vessel disease in 4 pa
tients (20%), and triple-vessel disease in 16 (80%). Two patients (10%
) had left main coronary artery stenosis, and 4 had previous recent my
ocardial infarction. All patients received unilateral carotid endarter
ectomy and a mean number of 3.5 distal anastomoses of coronary arterie
s. No patient died within thirty days after simultaneous operation, an
d operative mortality rate was zero. The late mortality rate was 20%,
with only 1 death related to myocardial infarction and 1 attributable
to contralateral stroke. According to a proposed guideline, the long-t
erm outcome is determined by the extent and severity of the cardiovasc
ular disease. Simultaneous operation is appropriate for a subgroup of
patients with coexisting carotid and coronary artery disease.