CHROMOGENIC LACTATE-LEUKOCYTE ESTERASE SUBSTRATES

Authors
JOHNSON GM SCHAEPER R
Citation
Gm. Johnson et R. Schaeper, CHROMOGENIC LACTATE-LEUKOCYTE ESTERASE SUBSTRATES, Bioconjugate chemistry, 8(1), 1997, pp. 76-80
Citations number
28
Categorie Soggetti
Biology,Chemistry,"Biochemical Research Methods
Journal title
Bioconjugate chemistry → ACNP
ISSN journal
10431802
Volume
8
Issue
1
Year of publication
1997
Pages
76 - 80
Database
ISI
SICI code
1043-1802(1997)8:1<76:CLES>2.0.ZU;2-8
Abstract
The First successful reported use of lactate-based chromogenic, colori metric substrates for a serine protease-based enzyme is described. A s eries of hydroxy-protected 5-phenyl-3-hydroxypyrrolyl L-lactate substr ates of the general formula RO-Lac-OPP were prepared and formulated in to reagents for the determination of leukocytes in dry phase formats.