BILATERAL SUBTHALAMIC NUCLEUS STIMULATION FOR SEVERE PARKINSONS-DISEASE

Authors
LIMOUSIN P POLLAK P BENAZZOUZ A HOFFMANN D BROUSSOLLE E PERRET JE BENABID AL
Citation
P. Limousin et al., BILATERAL SUBTHALAMIC NUCLEUS STIMULATION FOR SEVERE PARKINSONS-DISEASE, Movement disorders, 10(5), 1995, pp. 672-674
Citations number
17
Categorie Soggetti
Clinical Neurology
Journal title
Movement disorders → ACNP
ISSN journal
08853185
Volume
10
Issue
5
Year of publication
1995
Pages
672 - 674
Database
ISI
SICI code
0885-3185(1995)10:5<672:BSNSFS>2.0.ZU;2-X
Abstract
Subthalamic nucleus (STN) lesions or high-frequency stimulations could improve parkinsonian symptoms in monkeys treated by MPTP. We have app lied the procedure of chronic stimulation to the STN in severely disab led parkinsonian patients. This article presents the case of the first patient operated on bilaterally. Bilateral STN stimulation has greatl y improved akinesia and rigidity. The benefit was maintained less than or equal to 15 months after surgery. Unilateral stimulation induced m otor effects mainly in contralateral limbs. Further studies are needed to evaluate the value of this procedure in the treatment of Parkinson 's disease.