CORNEAL ENDOTHELIAL PERMEABILITY IN PROTECTION GLAUCOMA FILTER BLEB WITH TISSUE-PLASMINOGEN ACTIVATOR

After glaucoma filtering surgery subconjunctival injection of human re combinant tissue plasminogen activator may promote the function of gla ucoma filter bleb and increase outflow facility. It can also increase postoperative complications, such as corneal damage. The aim of our re search was to determine corneal endothelial permeability (Pac) in subj ects with glaucoma filter bleb protected by a plasminogen activator (A ctilyse, Boehringer) when haemorrhagic clots obstructing a glaucoma fi ltering site had occurred. Two weeks, three months and six months afte r goniotrephining with scleral cover, in groups with and without subco njunctival injection of 25 mg human tissue plasminogen activator, Pac was calculated. In both groups, no significant differences in the leve l of Pac measured by fluorophotometry were found.