The present study deals with the retinal vascular involvement in 64 pa
tients with toxoplasmic retinochoroiditis during the acute phase of th
e disease and its evolution. Vascular involvement was noted in all 64
eyes during the acute phase of the disease. In 59 (92%) out of 64 case
s the vascular involvement was located in the same retinal quadrant as
the active toxoplasmic lesion. In the remaining 5 eyes (8%) the vascu
lar participation was found in all four retinal quadrants. In 3 (5%) o
ut of 64 cases, the vascular infiltration was extremely severe and res
ulted in retinal vascular obstruction. In all three cases the vessel t
raversed the active toxoplasmic lesion. In 35 (55%) out of 64 patients
the initial vascular picture changed in the course of the acute phase
of the disease. In these patients, the lesions had extended to the ad
jacent vessels or to other parts of the involved vessel. In the furthe
r course of the evolution of the active toxoplasmic lesion, the vascul
ar involvement did not persist indiscriminately. It was noted that in
14 (22%) out of 64 cases the vascular lesions gradually regressed and
eventually disappeared together with the active toxoplasmic lesion and
the formation of the retinochoroidal scar. In the remaining 50 (78%)
out of 64 cases the vascular involvement either disappeared after the
establishment of the retinochoroidal scar in 3-12 months (29 cases) or
remained permanently (21 cases).