ACUTE LYMPHOBLASTIC-LEUKEMIA WITH A UNIQUE TRANSLOCATION IN AN ADOLESCENT BOY

Citation
A. Ballin et al., ACUTE LYMPHOBLASTIC-LEUKEMIA WITH A UNIQUE TRANSLOCATION IN AN ADOLESCENT BOY, Cancer genetics and cytogenetics, 83(1), 1995, pp. 90-92
Citations number
10
Categorie Soggetti
Oncology,"Genetics & Heredity
ISSN journal
01654608
Volume
83
Issue
1
Year of publication
1995
Pages
90 - 92
Database
ISI
SICI code
0165-4608(1995)83:1<90:ALWAUT>2.0.ZU;2-K
Abstract
We report a case of an adolescent boy with acute lymphoblastic leukemi a whose blasts had three chromosomal abnormalities: trisomy 8, a t(5;1 5), and an extra ''marker'' chromosome. The patient presented with hug e hepatosplenomegaly and pancytopenia. The response to treatment (ALL BFM 90 protocol) was very rapid, and the patient is in complete remiss ion 1 year after diagnosis.