THE UTILITY OF CONTROLLED-RELEASE NORGESTOMET IMPLANTS IN SYNCHRONIZING ESTRUS AND DIAGNOSING PREGNANCY IN EWES, AND FACTORS AFFECTING THE DIFFUSION RATE OF NORGESTOMET FROM SILICONE IMPLANTS

Citation
Dj. Kesler et Rj. Favero, THE UTILITY OF CONTROLLED-RELEASE NORGESTOMET IMPLANTS IN SYNCHRONIZING ESTRUS AND DIAGNOSING PREGNANCY IN EWES, AND FACTORS AFFECTING THE DIFFUSION RATE OF NORGESTOMET FROM SILICONE IMPLANTS, Drug development and industrial pharmacy, 23(2), 1997, pp. 217-220
Citations number
11
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
ISSN journal
03639045
Volume
23
Issue
2
Year of publication
1997
Pages
217 - 220
Database
ISI
SICI code
0363-9045(1997)23:2<217:TUOCNI>2.0.ZU;2-U
Abstract
One hundred Suffolk and cross-bred ewes were implanted with norgestome t/silicone implants to assess efficacy and utility, and to determine f actors affecting norgestomet diffusion. The overall estrus and lambing responses were 90% and 67%, respectively. Administration of the impla nt for 14 days during pregnancy, in conjunction with progesterone dete rmination on the 14th day, permitted the diagnosis of pregnancy status with 100% accuracy. Norgestomet implantation had no adverse effects o n established pregnancy. implants that were movable in situ on the 14t h day had less connective tissue encapsulation and a higher (p < 0.05) norgestomet diffusion rate than implants that had rigid subcutaneous placement and more connective tissue encapsulation.