The incidence of unexplained deaths ('dead in bed syndrome') in Norweg
ian diabetic patients under the age of 40 was investigated during the
period 1981-1990. During this 10-year period there were 240 deaths of
all causes in the age group 0-39 years. Sixteen of these cases fulfill
ed the following criteria of the 'dead in bed syndrome': (1) patient f
ound dead in an undisturbed bed; (2) patient observed to be in good he
alth condition the day before; (3) no clinical evidence of late compli
cations (except background retinopathy in two cases). Of the 16 cases
ascertained, 10 were males and 6 females. The age range was 7-35 years
, and the duration of diabetes varied between a few months and 26 year
s. Autopsy, performed in 13 cases, did not reveal any cause of death.
Nine patients had been using insulin regimens with multiple daily dose
s. Twelve patients were reported as having had frequent episodes of hy
poglycaemia, with nocturnal episodes in 10 cases. There was apparently
an increasing incidence of unexplained deaths during the study period
, with 12 of 16 eases occurring in the years 1988 to 1990.