Hq. Liu et al., NOVEL LUMINESCENT CYCLOMETALATED AND TERPYRIDINE GOLD(III) COMPLEXES AND DNA-BINDING STUDIES, Journal of the Chemical Society, Chemical Communications, (17), 1995, pp. 1787-1788
Two gold complexes, [Au-III{4-MeOPh-(Phbipy)}Cl]. CF3SO3 1 and [Au-III
(4-MEOPh-terpy)Cl].(ClO4)(2) 2 [4-MeOPh-(Phbipy) = 4'-(4-methoxyphenyl
)-6'-phenyl-2,2'-bipyridine, 4-MeOPh-terpy = 4'-(4-methoxyphenyl)-2,2'
,6',2''-terpyridine] are prepared, and their interactions with calf-th
ymus DNA, poly(dG-dC)(2) and poly(dA-dT)(2), investigated by spectrosc
opic means; in the reaction with ct DNA, 1 has a higher binding consta
nt than 2, but the latter has a higher degree of AT specificity.