SEQUENCE-ANALYSIS OF A-9873 BP FRAGMENT OF THE LEFT ARM OF YEAST CHROMOSOME-XV THAT CONTAINS THE ARG8 AND CDC33 GENES, A PUTATIVE RIBOFLAVIN SYNTHASE BETA-CHAIN GENE, AND 4 NEW OPEN READING FRAMES

The DNA sequence of a 9873 bp fragment located near the left telomere of chromosome XV has been determined. Sequence analysis reveals seven open reading frames. One is the ARG8 gene coding for N-acetylornithine aminotransferase. Another corresponds to CDC33, which codes for the i nitiation factor 4E or cap binding protein. The open reading frame AOE 169 can be considered as the putative gene for the Saccharomyces cerev isiae riboflavin synthase beta chain, since its translation product sh ows strong homology with four prokaryotic riboflavin synthase beta cha ins. The nucleotide sequence reported here has been submitted to the E MBL data library under the Accession Number X84036.