R. Dhote et al., CENTRAL RETINAL VEIN-THROMBOSIS ASSOCIATED WITH RESISTANCE TO ACTIVATED PROTEIN-C, American journal of ophthalmology, 120(3), 1995, pp. 388-389
PURPOSE/METHODS: Activated protein C resistance was recently described
as a major cause of venous thrombosis. We observed a central retinal
vein thrombosis in a woman with activated protein C resistance. RESULT
S/CONCLUSION: DNA analysis showed the patient to be heterozygous for t
he factor V gene mutation, which is related to activated protein C res
istance. Patients with retinal vein thrombosis should be examined for
activated protein C resistance.