Ly. Shih et al., TOTAL HIP-ARTHROPLASTY IN PATIENTS WITH ANKYLOSING-SPONDYLITIS - LONG-TERM FOLLOW-UP, Journal of rheumatology, 22(9), 1995, pp. 1704-1709
Objective. To evaluate the longterm functional effects of total hip ar
throplasty (THA) on 46 patients. Methods. Clinical and radiographic ex
aminations were performed on 46 patients (74 THA) with ankylosing spon
dylitis (AS). The mean followup period was 100 months (range 37-174 mo
nths); 32 hips were followed for more than 10 years. Results. Signific
ant benefit was obtained in pain control (all but 2) and function (mea
n improvement in range of motion 128 degrees) in the early stage so th
at patients could be gainfully employed. An average 100 months after T
HA, the overall functional results were rated excellent in 21 hips, go
od in 28, fair in 7, and poor in 18, Only 6 hips (8%) in our series de
veloped clinically significant (Class III or IV) heterotopic ossificat
ion. Seventeen hips needed a 2nd operation because of loosening (11 hi
ps), deep infection (3), malposition of acetabular component (2), and
prosthetic failure (1). Another 6 hips showed definite loosening on ra
diographs and needed to be revised. The total incidence of failure was
31% (23 hips). The average time from the index operation to loosening
was 9.5 years (range 4-13 years). Factors contributing to component l
oosening were young age, short stature, and decreased postoperative ra
nge of motion. Conclusion. Total hip arthroplasty can be very importan
t and beneficial to patients with AS, but the patients, being young an
d active, and with their rigid spines, do not treat their prostheses g
ently and are very dependent upon their mobility. They must be kept un
der supervision long after THA, probably for the rest of their lives,
to identify possible longterm complications.