FUSED PYRIDINE-DERIVATIVES FROM THE WITTIG REACTION OF SOME FLUORINATED AMIDES

Authors
LATHAM EJ MURPHY SM STANFORTH SP
Citation
Ej. Latham et al., FUSED PYRIDINE-DERIVATIVES FROM THE WITTIG REACTION OF SOME FLUORINATED AMIDES, Tetrahedron, 51(37), 1995, pp. 10385-10388
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
37
Year of publication
1995
Pages
10385 - 10388
Database
ISI
SICI code
0040-4020(1995)51:37<10385:FPFTWR>2.0.ZU;2-B
Abstract
Compound 2 reacted with phosphorane 3 (R = Et) giving the quinoline de rivative 5 whereas thiophenes 7 and 9 gave enamines 8 and 10 respectiv ely with the appropriate phosphorane 3 (R = Me or Et). Pyridine deriva tive 11 yielded only ethyl 2-aminonicotinate with phosphorane 3 (R = E t). Compounds 8 and 10 gave the fused pyridine derivatives 14 and 15 r espectively when treated with sodium hydride.