T. Knoos et al., LIMITATIONS OF A PENCIL BEAM APPROACH TO PHOTON DOSE CALCULATIONS IN LUNG-TISSUE, Physics in medicine and biology, 40(9), 1995, pp. 1411-1420
A common limitation in treatment planning systems for photon dose calc
ulation is to ignore the impact on electron transport and photon scatt
er from patient heterogeneities. The heterogeneity correction is often
based on scaling operations along beam rays as for the method accordi
ng to Bathe or the more novel approach of 1D convolutions along beam p
aths applied in pencil-beam-based systems. The effects of the limitati
on have been studied in a mediastinium geometry for a wide range of be
am qualities by comparing the results from a pencil-beam-based treatme
nt planning system with the results from Monte Carlo calculations. As
expected, the deviations within unit-density volumes are small while d
eviations in low-density volumes increase with increasing beam energy
from approximately 3% for 4 MV to 14% for 18 MV x-rays as a result of
increased electron disequilibrium.