STUDIES ON THE RELATIONSHIP BETWEEN ADHESIVE ACTIVITY AND HEMAGGLUTINATION BY HELICOBACTER-PYLORI

The adhesion of Helicobacter pylori to gastric carcinoma cells (MKN45, KatoIII and MKN28) and Intestine-407 cells was tested by flow cytomet ric analysis. The mean adhesion rates of H. pylori strains to MKN45, K atoIII and Intestine-407 cells were 90.5, 42.7 and 15.1%, respectively , There was no statistical correlation between the adhesion rates to M KN45 cells and haemagglutination (HA) activity of H. pylori strains, a lthough H. pylori strains with high HA activity with human type O eryt hrocytes tended to adhere effectively to MKN45 cells. No correlation b etween adhesion and production of vacuolating toxin was observed.