R. Schlenker et al., AFFECTIVE MODULATION OF THE STARTLE REFLEX IN SCHIZOPHRENIC-PATIENTS, European archives of psychiatry and clinical neuroscience, 245(6), 1995, pp. 309-318
Startle-elicited blinks were measured during the presentation of affec
tive slides in order to investigate emotional responsiveness in 24 mal
e healthy subjects and 34 male schizophrenic patients. Although the tw
o groups did not differ with regard to their subjective and autonomic
responses to the slide stimuli, there was a significant difference bet
ween the groups in their responses to the startle probes. Patients rat
ed low in affective expression showed a linear response pattern compar
able to that of normal controls with largest amplitudes during unpleas
ant slides and smallest during pleasant slides. Patients without appar
ent deficit in affective expression showed a quadratic relationship wi
th smaller blink amplitudes during both pleasant and unpleasant slides
. Diminished affective expression rated on the basis of a clinical int
erview is not associated with a general attenuation of the blink refle
x or of its modulation by exposure to emotional slides. Thus, we found
no indication of an impairment in the perception of affective stimuli
nor of reduced appreciation of pleasant stimuli (anhedonia) in these
patients.