Objective: To compare laparotomy closure with interrupted polyglactin
910 (Vicryl) and continuous polydioxanone (PDS II), and assess the mec
hanical and other factors that influenced the incidence of burst abdom
en. Design: Retrospective study. Setting: University hospital, The Net
herlands. Subjects: A random sample of 346 patients who did not burst
their abdomens, taken from the total of 3768 patients who underwent pr
imary midline laparotomy from 1986-1990, together with the 45 (1%) fro
m the total series who did burst their abdomens. Main outcome measures
: Incidence of burst abdomen, and the association with mechanical and
others risk factors. Results: There were no differences in the inciden
ce of burst abdomen between those sutured with interrupted polyglactin
910 and those sutured with continuous polydioxanone (p = 0.12). Layer
ed closure resulted in significantly more burst abdomens than any othe
r method of closure (p < 0.001 in each case). Postoperative wound infe
ction (14/43, 33%, compared with 33/343 10%) and pulmonary complicatio
ns (25/43, 58%, compared with 44/344, 13%) were also significantly ass
ociated with the development of burst abdomens (p < 0.001). Conclusion
s: A continuous, monofilament, absorbable suture should be used to clo
se a laparotomy incision. Elastic suture material, loop sutures, an th
e continuous figure-of-eight technique should be investigated.