MYCOSIS-FUNGOIDES PALMARIS ET PLANTARIS

Background: Mycosis fungoides primarily localized to the palms and sol es is rare and has been previously reported as cutaneous lymphoma in f our patients or as Woringer-Kolopp disease in eight patients. Observat ions: Four patients were initially diagnosed and treated unsuccessfull y for various palmoplantar dermatitides until histopathologic findings revealed mycosis fungoides. Each case exhibited a clonal rearrangemen t of T-cell receptor gamma genes and immunohistochemical studies conso nant with mycosis fungoides. All patients had limited skin involvement without evidence of extracutaneous involvement. Conclusions: Mycosis fungoides palmaris et plantaris is an uncommon expression of mycosis f ungoides that manifests primarily on the palms and soles and clinicall y may mimic various inflammatory palmoplantar dermatoses. A biopsy is recommended in the evaluation of recalcitrant palmoplantar dermatoses.