HYLSULFONYL-3-PHENYLFURO[3,4-D]ISOXAZOLE-4(6H)-ONE - A USEFUL SYNTHONFOR PREPARATION OF HETEROANTHRACYCLINONE ANALOGS

Authors
ALGUACIL R FARINA F MARTIN MV PAREDES MC
Citation
R. Alguacil et al., HYLSULFONYL-3-PHENYLFURO[3,4-D]ISOXAZOLE-4(6H)-ONE - A USEFUL SYNTHONFOR PREPARATION OF HETEROANTHRACYCLINONE ANALOGS, Tetrahedron letters, 36(37), 1995, pp. 6773-6776
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
37
Year of publication
1995
Pages
6773 - 6776
Database
ISI
SICI code
0040-4039(1995)36:37<6773:H-AUS>2.0.ZU;2-W
Abstract
The synthon 6 was prepared from 4,5-diethylsulfonylfuran-2(5H)one (4) by 1,3-dipolar cycloaddition of benzonitrile oxide. Annelation of diff erently functionalized quinone monoketals with the anion of the isoxaz ole 6 affords a range of heteroanthracyclinone analogues.