MODIFIED OLIGONUCLEOTIDES - EFFECT OF 4-ATOM VS 5-ATOM CHIMERIC INTERNUCLEOSIDE LINKAGES ON DUPLEX STABILITY

Authors
STORK G ZHANG CZ GRYAZNOV S SCHULTZ R
Citation
G. Stork et al., MODIFIED OLIGONUCLEOTIDES - EFFECT OF 4-ATOM VS 5-ATOM CHIMERIC INTERNUCLEOSIDE LINKAGES ON DUPLEX STABILITY, Tetrahedron letters, 36(36), 1995, pp. 6387-6390
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
36
Year of publication
1995
Pages
6387 - 6390
Database
ISI
SICI code
0040-4039(1995)36:36<6387:MO-EO4>2.0.ZU;2-E
Abstract
The question whether a four or a five atom non phosphorus based intern ucleoside link leads to stronger binding of the resulting chimeric oli gonucleotides to complementary sequences has been examined by comparin g melting temperatures of relevant duplexes.