We undertook a mailing survey study to assess the current practice of
sedative premedication in anesthesia. A total of 5396 questionnaires w
ere mailed to randomly selected physician members of the American Soci
ety of Anesthesiologists. Forty-six percent (n = 2421) of those sample
d returned the questionnaire after two mailings. The reported rate of
sedative premedication in the United States varied widely among age gr
oups and geographical locations. Premedicant sedative drugs were least
often used with children younger than age 3 years and most often used
with adults less than 65 years of age (25% vs 75%, P = 0.001). Midazo
lam was the most frequently used premedicant both in adults and childr
en (>75%). When analyzed based on geographical locations, use of sedat
ive premedicants among adults was least frequent in the Northeast regi
on and most frequent in the Southeast region (50% vs 90%, P = 0.001).
When the frequency of premedication was examined against health mainte
nance organization (HMO) penetration (i.e., HMO enrollment by total po
pulation) in the various geographical regions, correlation coefficient
s (r) ranged from -0.96 to -0.54. Multivariable analysis revealed that
HMO penetration is an independent predictor for the use of premedicat
ion in adults and children. The marked variation among geographical ar
eas in premedicant usage patterns underscores the lack of consensus am
ong anesthesiologists about the need for premedication. The data sugge
st that HMO participation may affect delivery of this component of ane
sthetic care.