The neuropathology of parkinsonism is reviewed as it occurs in primary
(idiopathic) and secondary extrapyramidal syndromes. Present understa
nding of the significance of Lewy bodies in Parkinson's disease, diffu
se Lewy body disease, and Lewy body variant of Alzheimer's disease is
emphasized. The neuropathology produced by a variety of secondary caus
es is also considered to demonstrate the diverse lesions that can resu
lt in parkinsonism. (C) 1995 Academic Press, Inc.