Atypical and typical chest pains are common symptoms in patients with
hypertrophic cardiomyopathy. Some of these chest pains seem to be caus
ed by ischaemia. It is difficult to objectively demonstrate ischaemia
in hypertrophic cardiomyopathy. The first line treatment for chest pai
n considered to be ischaemic in patients with hypertrophic cardiomyopa
thy is the use of either a beta blocker or calcium blocker. Septal mye
ctomy can be effective in patients with symptoms refractory to convent
ional treatment but is associated with significant morbidity and morta
lity. Recently dual chamber pacing has been advocated in such patients
. In some cases dual chamber pacing alleviates chest pain in hypertrop
hic cardiomyopathy by an antiischaemic action, presumably by reducing
the left ventricular outflow tract gradient and perhaps by causing an
associated decrease in left ventricular outflow tract gradient and per
haps by causing an associated decrease in left ventricular end diastol
ic pressure.