TUBULOINTERSTITIAL NEPHRITIS IN CHRONIC V IRAL DISEASES OF THE LIVER

In 8 patients with chronic renal failure (CRF) on hemodialysis combine d therapy (erythropoietin+calcitriol) effect was evaluated versus cont rol group of 9 hemodialysis patients on erythropoietin monotherapy. In patients on tile combined regimen the antianemic effect occurred soon er, this effect of calcitriol coming prior to correction of uremic def ects in phosphoric-calcium metabolism. Calcitriol mechanisms of action in renal anemia and benefits of potential calcitriol+erythropoietin c ombination use in CRF patients suffering from uremic osteodystrophy, h ypercatabolic conditions, uremic hypogonadism and infection complicati ons are discussed.