Zs. Alekberova et al., VASCULOPATHY IN PATIENTS WITH SYSTEMIC LU PUS-ERYTHEMATOSUS WITH ANTIPHOSPHOLIPID SYNDROME (APS), Terapevticeskij arhiv, 67(5), 1995, pp. 41-44
Clinicomorphological examination covered 100 patients with confirmed S
LE: 79 with concomitant APS (group 1), 21 free of APS (group 2). In gr
oup 1 thrombolytic complications occurred in 75%, in group 2 - in 13%.
The recurrences were more frequent in group 1. Overall percentage of
arterial and venous thromboses was approximately the same. According t
o biopsy and autopsy 2 kinds of morphological changes were found: typi
cal for SLE and APS. Morphological specificity of APS manifested with
proliferative and thrombotic changes in both arteries and veins.