QUALITY ASSURANCE IN CERVICAL CYTOLOGY SCREENING - COMPARISON OF RAPID RESCREENING AND THE PAPNET TESTING SYSTEM

OBJECTIVE: To assess the performance of the PAPNET Testing System and compare the sensitivity of this automated device with that of rapid re screening. STUDY DESIGN: In this study, 1,000 cervical smears previous ly diagnosed by our laboratory as negative were seeded with 20 particu larly ''difficult'' cases. We submitted this seeded set of smears for rapid rescreening and to PAPNET to determine cases that could be detec ted by rapid rescreening, PAPNET or both. RESULTS: Rapid rescreening d etected 9 of the 20 cases (45%). The PAPNET system identified 19/20 (9 5%). This investigation found PAPNET rescreening to be more effective than rapid rescreening in detecting the seeded difficult cases. CONCLU SION: Use of the PAPNET Testing System in tandem with rapid rescreenin g can reduce the rate of false negatives in diagnostically difficult c ervical cytologic smears.