ONLINE LIQUID-CHROMATOGRAPHY NUCLEAR-MAGNETIC-RESONANCE MASS-SPECTROMETRY - A POWERFUL SPECTROSCOPIC TOOL FOR THE ANALYSIS OF MIXTURES OF PHARMACEUTICAL INTEREST

Authors
PULLEN FS SWANSON AG NEWMAN MJ RICHARDS DS
Citation
Fs. Pullen et al., ONLINE LIQUID-CHROMATOGRAPHY NUCLEAR-MAGNETIC-RESONANCE MASS-SPECTROMETRY - A POWERFUL SPECTROSCOPIC TOOL FOR THE ANALYSIS OF MIXTURES OF PHARMACEUTICAL INTEREST, Rapid communications in mass spectrometry, 9(11), 1995, pp. 1003-1006
Citations number
7
Categorie Soggetti
Spectroscopy,"Chemistry Analytical
Journal title
Rapid communications in mass spectrometry → ACNP
ISSN journal
09514198
Volume
9
Issue
11
Year of publication
1995
Pages
1003 - 1006
Database
ISI
SICI code
0951-4198(1995)9:11<1003:OLNM>2.0.ZU;2-K
Abstract
Liquid chromatography (LC), simultaneously coupled with both nuclear m agnetic resonance (NMR) and mass spectrometry (MS) 'on-line' is a powe rful structural tool and has a potentially vast range of uses within t he pharmaceutical industry. Data from a mixture of fluconazole and rel ated triazoles have been obtained from an LC/NMR-MS system developed ' in-house', demonstrating the power of this novel analytical approach.