DETERMINATION OF THE MINIMUM DOSE OF LACTOSE DRUG CARRIER THAT CAN BESENSED DURING INHALATION

Authors
HIGHAM MA SHARARA AM MAGEE RP IND PW
Citation
Ma. Higham et al., DETERMINATION OF THE MINIMUM DOSE OF LACTOSE DRUG CARRIER THAT CAN BESENSED DURING INHALATION, British journal of clinical pharmacology, 40(3), 1995, pp. 281-282
Citations number
5
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
British journal of clinical pharmacology → ACNP
ISSN journal
03065251
Volume
40
Issue
3
Year of publication
1995
Pages
281 - 282
Database
ISI
SICI code
0306-5251(1995)40:3<281:DOTMDO>2.0.ZU;2-G
Abstract
Lactose is commonly used as a carrier for inhaled drugs. Twenty health y volunteers without respiratory: symptoms inhaled seven different dos es of. lactose and a placebo (empty) dose through the four place Diskh aler(R) device, in order to determine the lowest dose that could be re liably sensed. The minimum dose for which all subjects reported taste or feel sensations was 10 mg. This has implications regarding the amou nt of carrier used in future drug delivery systems.