Ns. Abramson et al., HOW GOOD ARE VOLUNTEERS AT SEARCHING FOR PUBLISHED RANDOMIZED CONTROLLED TRIALS, Fundamental and clinical pharmacology, 9(4), 1995, pp. 384-386
The Ottawa Stroke Trials Registry (OSTR) collects information on all r
andomized controlled trials (RCTs), in all languages, in which the pri
mary focus is stroke. Published trials are added to the registry datab
ase once they have been identified by volunteers hand searching journa
ls. We undertook this study to assess volunteer sensitivity, specifici
ty, positive and negative predictive values, accuracy and reliability
in identifying RCTs. Three volunteers participated in this study. The
complete contents of five years of one journal were searched (n = 240)
as were ten research reports from five journals. Volunteer sensitivit
y, specificity, positive and negative predictive values, and accuracy
was 89.5%, 100%, 100%, 99.1%, and 99% respectively. Inter volunteer re
liability was 0.87. Searching the published literature to identify RCT
s is an enormous task. These results indicate that volunteers, with mi
nimal training, can effectively contribute to this endeavour.