GRANULOMATOUS BONE-MARROW INFLAMMATION DURING TREATMENT OF CHRONIC MYELOID-LEUKEMIA WITH INTERFERON-ALPHA-2B

Authors
SIBONI A MOURITSANDERSEN T MOESNER J
Citation
A. Siboni et al., GRANULOMATOUS BONE-MARROW INFLAMMATION DURING TREATMENT OF CHRONIC MYELOID-LEUKEMIA WITH INTERFERON-ALPHA-2B, Journal of Clinical Pathology, 48(9), 1995, pp. 878-880
Citations number
8
Categorie Soggetti
Pathology
Journal title
Journal of Clinical Pathology → ACNP
ISSN journal
00219746
Volume
48
Issue
9
Year of publication
1995
Pages
878 - 880
Database
ISI
SICI code
0021-9746(1995)48:9<878:GBIDTO>2.0.ZU;2-G
Abstract
A patient with chronic myeloid leukaemia developed bone marrow granulo mas during treatment with interferon alpha-2b. Some granulomas had nec rotic centres and giant cells and there was marked eosinophilia surrou nding them, The granulomas disappeared when the interferon treatment w as discontinued. Mycobacteriosis was ruled out. The most Likely explan ation for the granuloma formation was drug hypersensitivity.