C. Stollberger et al., ELAT STUDY (EMBOLISM IN LEFT ATRIAL THROMBI) - BASE-LINE CLINICAL ANDECHOCARDIOGRAPHIC DATA, Cardiology, 86(6), 1995, pp. 457-463
By transesophageal echocardiography, the prevalence of left atrial/app
endage thrombi and spontaneous echo contrast and the size of the left
atrial appendage and their association with clinical and echocardiogra
phic characteristics were evaluated in 409 nonrheumatic atrial fibrill
ation outpatients (62 +/- 12 years) without recent (<1 year) embolism.
Left atrial/appendage thrombi (2.5%) were associated with diabetes (p
< 0.05), heart failure (p < 0.05) and low fractional shortening (p <
0.001); spontaneous echo contrast (12%) with advanced age (p < 0.01),
constant atrial fibrillation (p < 0.01), hypertension (p < 0.01), hear
t failure (p < 0.05), valvular abnormalities (p < 0.01) and large left
atrial diameter (p < 0.01), and large left atrial appendages with con
stant atrial fibrillation (p < 0.05), diabetes (p < 0.05) and valvular
abnormalities (p < 0.05).