P. Teal et al., CORNEAL SUBEPITHELIAL INFILTRATES FOLLOWING EXCIMER-LASER PHOTOREFRACTIVE KERATECTOMY, Journal of cataract and refractive surgery, 21(5), 1995, pp. 516-518
Corneal subepithelial opacification associated with pain, photophobia,
and injection has been reported in the first to third day following p
hotorefractive keratectomy (PRK). Regardless of treatment, the resolut
ion has generally left the patient with permanent corneal scarring and
a one to two line reduction in visual acuity. We surveyed 50 PRK surg
eons and received responses from 17 on 30 cases of this complication,
which occurs in approximately one in 300 cases. The etiology is unknow
n. Cases were first reported when nonsteroidal anti-inflammatory drugs
, with or without occlusive contact lens, were substituted for convent
ional bandage occlusion in the postoperative protocol for PRK.