ANEUPLOIDY OCCURRENCE IN HUMAN TUMORS - A LOGICAL-AUTOMATON APPROACH

The search for new, reliable factors of prognosis in cancerology is sa dly deficient at the present moment. Of these factors, the measurement of ploidy gives rise to considerable hope. Nevertheless, despite the impressive number of papers currently published, no general law seems to be emerging that associates the ploidy rate of a tumour with its cl inical evolution in a patient. The purpose of the present work is firs tly to use a logical automaton to describe the cell cycle in terms of binary variables (the validation of the methodology), and secondly to demonstrate that a certain 'cancer logic' can be distilled, at least w ith respect to the genesis of DNA histograms among rumours.