A FAST, RELIABLE, AUTOMATIC SHIMMING PROCEDURE USING H-1 CHEMICAL-SHIFT-IMAGING SPECTROSCOPY

The importance and the difficulty of achieving good Be homogeneity ove r the volume of interest in in vivo NMR spectroscopy are well known A fast, reliable, versatile, and fully automatic shimming procedure has been developed, using 3D chemical-shift imaging to measure the field d istribution using only the water peak in the sample of interest, The p rocedure minimizes the mean-square error in the field distribution wit h respect to a constant held where the signal exists (e,g., the head). This produces a set of linear equations that can be solved by standar d matrix methods. The procedure has been applied on a commercial image r producing water linewidths from the entire head as low as 8 Hz at 1. 5 T. The mean linewidth and standard deviation from 94 head studies we re 11.7 +/- 1.9 Hz. (C) 1995 Academic Press, Inc.