OVARIAN AUTOIMMUNITY AND CORTICOTHERAPY IN AN IN-VITRO FERTILIZATION ATTEMPT

This case report describes a successful pregnancy and delivery in a wo man presenting with ovarian autoimmunity who had previously been invol ved in two unsuccessful in-vitro fertilization (IVF) attempts. Ten day s before a third attempt, she began a regimen of 25 mg per day of pred nisoione which was continued throughout the whole IVF protocol. Ovulat ion was induced by human menopausal gonadotrophin. After administratio n of 5000 IU of human chorionic gonadotrophin, 18 oocytes were collect ed. At 48 h after insemination with the patient's husband's spermatozo a, four 4-cell pre-embryos were transferred. A singleton pregnancy dev eloped and led to the birth of a girl who is doing well 10 months late r.