Jf. Guerin et al., IVF FAILURE RELATED TO HYPERACTIVATION DE FECTS OF SPERMATOZOA - INDICATION OF MICROINJECTION, Contraception fertilite sexualite, 23(7-8), 1995, pp. 466-467
Development of hyperactivated motility is considered as necessary for
penetration through zona pellucida. In a study concerning 114 IVF atte
mpts, we could not establish a significant correlation between fertili
zation rate and hyperactivation rate (HA). On the contrary, most ferti
lization failures (16/21) were found for HA values < 10%. 10 of such c
ouples could benefit of ICSI for the next attempt : fertilization rate
s were strictly similar to the general rate observed for ICSI in our g
roup (48%).