Purpose: The clinical assessment of pharmacologically induced erectile
response was compared to the real-time RigiScan monitoring response.
Materials and Methods: Erection was induced by 521 intracavernous inj
ections of a new alprostadil formulation. The clinical end point was '
'full rigidity'' and the RigiScan criterion was radial rigidity of 70%
or more for 10 consecutive minutes or longer. Results: For 752 prosta
glandin El injections the sensitivity and specificity of the RigiScan
device compared to clinical evaluation were 53.8% (133 of 247 cases) a
nd 92.9% (469 of 505), respectively. For rigidity of 60% or greater th
e sensitivity increased to 70.8% (175 of 247 cases) and specificity de
creased to 85.0% (429 of 505). Conclusions: The RigiScan device is use
ful to document objectively a pharmacologically induced erection yet i
t appears to be more conservative than clinical evaluation.