CHRONIC BRONCHOBRONCHIOLITIS OBLITERANS ASSOCIATED WITH STEVENS-JOHNSON SYNDROME

We report a case of bronchobronchiolitis obliterans associated with St evens-Johnson syndrome diagnosed using bronchography and bronchoscopy in a 25-year-old man with dyspnea. Eighteen months prior to admission, the diagnosis of Stevens-Johnson syndrome due to anticonvulsant thera py was made at another hospital. On admission, the patient was wheezin g and had overinflation of the lungs, with marked obstructive pulmonar y dysfunction. Ventilation and perfusion scintigrams revealed multiple ventilation and perfusion defects but not mismatch. Bronchography rev ealed central bronchiectasis and obstruction of the peripheral bronchi . Occlusion of the fifth right basal bronchus was observed with fibero ptic bronchoscopy. Bronchography and bronchoscopy provide useful infor mation for the diagnosis of this disease.