25-year-old man was admitted with complaints of fever and macrohematur
ia, Laboratory tests showed a substantial increase in serum creatine p
hosphokinase and creatinine in association with myoglobinuria and prot
einuria. Blood culture grew Streptococcus salivarius and Streptococcus
oralis. Findings of renal biopsy were compatible with IgA nephropathy
. The glomeruli had a mild mesangial proliferation without crescentic
lesions. Changes of the interstitium and tubules were not evident. The
clinical course and laboratory results strongly suggested a possible
link between Streptococcus salivarius/oralis infection, and rhabdomyol
ysis. Rhabdomyolysis is rarely seen as a complication of bacterial inf
ection, and the present case emphasizes the importance of suspecting b
acteremia due to Streptococcus salivarius/oralis in the presence of rh
abdomyolysis.