ENANTIOMER SEPARATION VIA DIASTEREOISOMERIC SALT FORMATION AND LIQUID-LIQUID PHASE-TRANSITION

Authors
ACS M KOZMA D FOGASSY E
Citation
M. Acs et al., ENANTIOMER SEPARATION VIA DIASTEREOISOMERIC SALT FORMATION AND LIQUID-LIQUID PHASE-TRANSITION, ACH, models in chemistry, 132(3), 1995, pp. 475-478
Citations number
6
Categorie Soggetti
Chemistry
Journal title
ACH, models in chemistry → ACNP
ISSN journal
12178969
Volume
132
Issue
3
Year of publication
1995
Pages
475 - 478
Database
ISI
SICI code
1217-8969(1995)132:3<475:ESVDSF>2.0.ZU;2-O
Abstract
On reacting racemic amine bases with half equivalent amount of sodium- hydrogen-tartrate in a water-benzene solvent system, the mixed-neutral tartrate accumulates in the aqueous phase, while the free base concen trates in the organic phase, resulting in enantiomer separation withou t crystallization.