Background. Controversy about operative morbidity and oncologic value
of bilobectomy has led to a review of our experience over the past 12
years. Methods. The charts of 112 patients (100 men and 12 women with
a mean age of 63 years) were reviewed for operative mortality and morb
idity and long-term survival. Survival of patients with stage I or sta
ge II disease was compared with that of stage-matched and age-matched
groups having right pneumonectomy. Results. Four patients (3.5%) died
postoperatively. Nonfatal complications occurred in 55 patients (49%);
the most frequent problem was pleural space disease (34%). Survival s
tudies focused on the 96 patients with nonsmall cell bronchogenic canc
er (44 in stage I, 32 in stage II, and 20 in stage IIIA). The overall
5-year survival rate was 40%; the 5-year survival rate was similar for
stage I and stage II (41% for stage I, 50% for stage II, and 17% for
stage IIIA). The incidence of local recurrence was significantly incre
ased after bilobectomy for stage I cancer (chi(2) = 5.066; p < 0.05) c
ompared with pneumonectomy but did not affect 5-year survival. Local r
ecurrence and survival were similar after bilobectomy and pneumonectom
y in stage II. Conclusions. These data demonstrate an increased morbid
ity after bilobectomy. Survival studies demonstrate an increased risk
of local recurrence in patients with stage I disease, which might be p
artly explained by understaging.