Arginine-vasopressin as well as luteinizing hormone (LH)/follicle-stim
ulating hormone (FSH) stimulate. progesterone release in superfused hu
man granulosa cells. Extracellular administration of inositol trisphos
phate (10(-6) mol/l) or calcium ions (10(4) mol/l) mimics the action o
f both arginine-vasopressin and LH/FSH and evokes progesterone secreti
on in superfused granulosa cells.