INDUCTION OF TH2 RESPONSES IN INFECTIOUS-DISEASES

Citation
Ej. Pearce et Sl. Reiner, INDUCTION OF TH2 RESPONSES IN INFECTIOUS-DISEASES, Current opinion in immunology, 7(4), 1995, pp. 497-504
Citations number
67
Categorie Soggetti
Immunology
ISSN journal
09527915
Volume
7
Issue
4
Year of publication
1995
Pages
497 - 504
Database
ISI
SICI code
0952-7915(1995)7:4<497:IOTRII>2.0.ZU;2-X
Abstract
Recent work on T-helper (Th) cell subset maturation has focused on def ining the cellular source of early IL-4, which promotes precursor (nai ve) CD4(+) Th cells to differentiate into Th type 2 (Th2) cells, and a lso on the roles of counter-regulatory cytokines, costimulatory signal s, and antigen in the induction of Th2 responses. Results suggest that not all Th2 cells are equivalent in their ontogeny.